Nucleic acid synthesis for investigations of gene functions. |
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| Authors: | E Ohtsuka |
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| Affiliation: | Health Sciences University of Hokkaido, Japan. |
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| Abstract: | The chemical syntheses of genes encoding human c-Ha-ras and T4 endonuclease V are described. These genes have been used for studies of mutagenesis by damaged bases and recognition of nucleic acids by proteins. The modes of interaction of photo-damaged DNA and cognate antibodies have also been investigated by biochemical and physicochemical approaches. |
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