House dust mite allergens in domestic homes in Cheonan, Korea |
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Authors: | Nam Hae-Seon Siebers Robert Lee Sun-Hwa Park Joon-Soo Kim Yong-Bae Choi Young-Jin Lee Sang-Han Crane Julian |
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Institution: | Department of Clinical Parasitology, School of Medicine, Soonchunhyang University, Cheonan 330-090, Korea. |
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Abstract: | House dust mites produce inhalant allergens of importance to allergic patients. We measured the major group 1 allergens, Der p 1 and Der f 1, from the house dust mites Dermatophagoides pteronyssinus and Dermatophagoides farina, respectively in 100 randomly selected domestic homes from Cheonan, Korea. Dust samples were collected by vacuuming from the living room floor and 1 mattress in each home. Der p 1 and Der f 1 were measured by double monoclonal ELISA. Der p 1 levels were very low, with geometric mean levels for floors and mattresses being 0.11 microgram/g (range: 0.01-4.05) and 0.14 microgram/g (range: 0.01-30.0), respectively. Corresponding levels of Der f 1 were higher, 7.46 microgram/g (range: 0.01-262.9) and 10.2 microgram/g (range: 0.01-230.9) for floors and mattresses, respectively. D. farinae appears to be the dominant house dust mite in Cheonan. |
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Keywords: | Dermatophagoides pteronyssinus Dermatophagoides farina house dust mite allergen asthma Korea |
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