Genetic experiments with model populations: Fallacies in genetic analysis performed from samples of recombinants selected for two markers

Abstract: Samples selected for two markers (one from each parent) from the progeny of a genetic cross are altered both in the genotype and in the frequency distribution as compared to the original progeny population. The consequences of these alterations were analyzed in selected samples obtained from model progeny populations of hypothetical genetic crosses. In complete progeny populations, distribution of genotypes (pattern of genotypes), sequence of markers, and frequency distribution of individual genotypes exhibit genetically intelligent relationship to each other only under a sole condition: at the correct sequence of markers. In selected samples, the singularity of the interrelationship is relaxed. Consequences of the relaxation in the genetic analysis are multiple, the most striking of which is an insinuation of circularity for the linear gene map.