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Genetic control of interleukin-2 production in inbred mice |
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| Authors: | A L Pukhal'ski? A P Toptygina |
| Abstract: | BALB/c mice (H-2d haplotype) produced IL 2 better than C57BL/6 mice (H-2d haplotype). However genetic analysis in F2 generation demonstrated independent segregation of the IL 2 production intensity and H-2 haplotype. Investigation of the IL 2 production intensity in BALB/c, C57BL/6 and their F1 and F2 generation revealed that this was controlled by only one gene. |
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