Genetic markers in Malaysians: Variants of soluble and mitochondrial glutamic oxaloacetic transaminase and salivary and pancreatic amylase,phosphoglucomutase III and saliva esterase polymorphisms |
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| Authors: | Y S Teng S G Tan C G Lopez Thomas Ng L E Lie-Injo |
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| Institution: | (1) University of California International Center for Medical Research, Kuala Lumpur, Malaysia;(2) Department of Biology, Universiti Pertanian Malaysia, Serdang, Selangor;(3) National Blood Transfusion Service Center, Kuala Lumpur, Malaysia;(4) Maternity Hospital, General Hospital, Kuala Lumpur, Malaysia;(5) G. W. Hooper Foundation, University of California, San Francisco, California, USA |
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| Abstract: | Summary Malaysians of Malay, Chinese, and Indian ancestries were electrophoretically phenotyped for Amy1 and saliva esterase region 1(Set-1) from saliva, Amy2 from plasma, soluble and mitochondrial GOT and PGM
3 from leukocyte and placenta. Kadazans and Bajaus, the indigenous people of Sabah, East Malaysia were surveyed for Amy2. Three types of variants were observed for Amy1, one type for Amy2. Only Indians were found to be polymorphic for Amy1. Two GOT
s 2-1 and three GOT
m 2-1 variants were found among 281 Chinese while three GOT
m 2-1 variants were found among 311 Malays.Malaysian Malays, Chinese, and Indians were found to be polymorphic for Set-1 and PGM
3. The gene frequencies in Malays are Set-1F=0.601±0.021, Set-1S=0.399±0.021; PGM
3
1
=0.788±0.020, PGM
3
2
=0.212±0.020; in Chinese Set-1F=0.497±0.028, Set-1S=0.503±0.028; PGM
3
1
=0.745±0.024, PGM
3
2
=0.255±0.024; in Indians, Set-1F=0.449±0.031, Set-1S=0.551±0.031; PGM
3
1
=0.755±0.029, PGM
3
2
=0.245±0.029. |
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