Supersizing the mitochondrial respiratory chain |
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Authors: | Shoubridge Eric A |
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Affiliation: | Department of Human Genetics, McGill University/MNI, Montreal, QC H3A 2B4, Canada. eric@ericpc.mni.mcgill.ca |
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Abstract: | The complexes of the mitochondrial respiratory chain assemble into higher-order structures called supercomplexes or respirasomes that are thought to be important in channeling electron flow and controlling ROS production. A number of recent papers identify the first protein factors necessary for supercomplex assembly and stability. |
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