CT全肝灌注的临床应用及进展

随着影像技术的发展和后处理功能的完善,肝灌注成像以研究组织、器官血流动力学变化已成为影像界关注的热点,然而CT灌注成像在肝脏等实质性器官中的应用尚处于探索阶段。肝脏具有双重血供,在各种病理生理情况下,肝脏动静脉之间及门静脉之间的血流动力学发生着复杂的变化。CT被认为是诊断肝脏病变最有价值的影像学方法,CT灌注成像能反映组织器官微循环内的血流动力学变化,是一种快速、准确、无创的功能成像方法。肝脏灌注CT检查可以同时获得形态和功能两方面的信息,使我们有可能早于形态学变化之前发现肝脏病变,有助于肝脏疾病的早期诊断和治疗,并能评价各种治疗手段对肝脏血流动力学变化的影响。本文针对全肝灌注CT扫描在临床的应用进行综述。

Progress and Application of CT Hepatic Perfusion

With the development of follow-up imaging technology and the improvement on the function of post-processing, liver perfusion imaging which studies the changement of tissue and organ hemodynamics has become a hot spot in the image field. However, the application of CT perfusion imaging in liver and other parenchymal organs are still at the exploration stage. The liver has a dual blood supply and the hemodynamics between hepatic artery and veins and portal vein changes complexly in a variety of physiological and pathological conditions. CT is considered as the most valuable imaging method about diagnosis of liver lesions. CT perfusion imaging which can reflect the changement of hemodynamic in tissues and organs microcirculation is a fast, accurate and noninvasive functional imaging method. Liver perfusion CT examination can also get the information of morphology and function at the same time, which can make us have a chance to find liver lesions earlier than morphological changes. It contributes to early diagnosis and treatment of liver diseases and evaluates that all kinds of treatment methods have influence on the changement of hepatic hemodynamics. This article discussed CT Perfusion imaging for whole liver in clinical application.