椎间植骨粒体积对腰椎滑脱融合内固定术融合效果的影响

目的:探讨在腰椎后路植骨融合手术中,椎间植骨粒的体积对手术效果的影响。方法:回顾性分析我院2012年5月-2013年9月采用腰椎后路植骨融合术的75例患者的临床资料,根据患者手术中椎间植骨粒体积不同分为A组(小体积组,5粒/cm3)、B组(中体积组,11粒/cm3)以及C组(大体积组,23粒/cm3)。分析三组患者的植骨粒体积、植骨融合率以及手术效果。结果:三组患者植骨粒体积比较,差异具有统计学意义(P0.05);椎间植骨总体积比较,差异无统计学意义(P0.05)。与术前比较,三组术后ODI指数及VAS评分明显下降,差异具有统计学意义(P0.05);但三组间比较,差异无统计学意义(P0.05)。B组植骨融合率高于A组及C组,而A组高于C组,组间比较,差异均具有统计学意义(P0.05)。手术后各组椎体滑脱程度与术前相比得到明显改善(P0.05)。结论:腰椎滑脱内固定术中应用中等体积植骨粒可明显提高椎体间融合率。

Effect of Bone Graft Volume on Intervertebral Fusion Fixation in the Spondylolisthesis

Objective:To explore the effects of the bone graft volume of grain interbody on the spondylolisthesis.Methods:75 patients with spondylolisthesis from May 2012 to September 2013 were selected and according to the different volumes of bone graft, the patients were divided into group A (small volume, 5/cm3), group B (moderate volume, 11/cm3) and group C (large volume, 23/cm3). Then the clinical data including volume, fusion rate, clinical results in patients with bone particles surgery in the three groups were analyzed.Results:The difference of bone graft volume was statistically significant difference among three groups (P<0.05). The volume of intervertebral bone graft was no statistically significant among three groups (P>0.05). Compared with before operation, postoperative ODI index and VAS score was decreased obviously in three groups with statistically significant difference (P<0.05); but there was no statistically significant difference among three groups (P>0.05). The fusion rate of bone graft was higher in group B than group A and group C, and it was higher in group A than that of group C, and the differences were statistically significant among groups (P<0.05). The degree of vertebral body slippage after surgery was improved significantly than before operation (P<0.05).Conclusion:In the internal fixation of spondylolisthesis surgery, the application of medium-volume bone graft can significantly improve the fusion rate.