糖化血红蛋白水平与急性缺血性脑卒中预后的相关性

目的：探讨糖化血红蛋白对急性脑梗死患者病情严重程度及预后的影响,为临床治疗提供科学依据。方法：将106例合并糖尿病的急性脑梗死患者根据其入院48h内HbA1c水平分为3组,对3组进行神经功能缺损评分、脑梗死损伤程度、治疗后疗效评价比较。结果：治疗前A组和B组神经功能缺损评分均明显高于C组（P〈0.05）,治疗后各组较治疗前均有所降低,但A组和B组神经功能缺损评分仍明显高于C组（P〈0.05）;入院时A组和B组脑梗死损伤程度中度、重度者明显高于C组（P〈0.05）;总有效率A组和B组明显低于C组,且A组与B组比较,A组明显低于B组（P〈0.05）,A组和B组脑梗死急性期加重率和死亡率明显高于C组（P〈0.05）;A组与B组相比,A组神经功能缺损评分、脑梗死损伤程度以及急性期加重率和死亡率明显高于B组,总有效率较B组低（P〈0.05）。结论：HbA1c水平与脑卒中的严重程度以及急性期预后不良密切相关,可以作为反映脑卒中发病时病情严重的指标之一。值得推广。

The Relation between the Level of Glycolated Hemoglobin and the Acute Cerebral Infarction

Objective： To investigate the relation between the level of glycolated hemoglobin（HbAlc） and acute cerebral infarction（ACI）.Methods： 106 cases of patients with ACI were divided into 3 groups,comparing the nervous function defect score,injury severity,treatment of cerebral infarction after therapeutic evaluation among three groups.Results： Treatment,neural function defect score in A group and B group were significantly higher than that in C group（P0.05）,after treatment,that was decreased,but the neural function defect score of A group and B group was significantly higher than that of C group（P0.05）;cerebral injury the extent of moderate,severe patients of A group and B group was higher than that of group C（P0.05）;the total efficiency of A group and B group was significantly lower than that in C group,and the total efficiency of A group was significantly lower than that in B group（P0.05）,cerebral infarction in the acute exacerbation rate and the mortality rate of A group and B group was significantly higher than that of C group（P0.05）;neural function defect score,injury severity and cerebral infarction in acute exacerbation rate and the mortality rate of A group were higher than those in the B group,the total efficiency was lower than that of B group（P 0.05）.Conclusion： HbAlc higher group and HbAlc most higher group are related with bad prognosis.