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Both R-loop removal and ribonucleotide excision repair activities of RNase H2 contribute substantially to chromosome stability
Institution:1. Department of Environmental and Radiological Health Sciences and Institute for Genome Architecture and Function, Colorado State University, Fort Collins, CO 80523, USA;2. Cell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, CO 80523, USA;1. Section on Formation of RNA, Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA;1. Department of Molecular and Cellular Biology and Genome Center, 1 Shields Avenue, University of California, Davis, Davis, CA 95616, USA;2. Department of Mathematical Modeling, Statistics, and Bioinformatics, University of Ghent, Ghent 9000, Belgium;1. Biochemistry Ph.D. Program, Florida International University, Miami, Florida, USA;2. Department of Chemistry and Biochemistry, Florida International University, Miami, Florida, USA;3. Biomolecular Sciences Institute, Florida International University, Miami, Florida, USA;4. Department of Biology, Indiana Purdue University Indianapolis, Indianapolis, Indiana, USA;5. Department of Biology, Tufts University, Medford, Massachusetts, USA;1. Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA;2. Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
Abstract:
Keywords:Ribonucleotides  R-loops  RNase H2  Loss-of-heterozygosity (LOH)
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