Quorum sensing by the Lyme disease spirochete |
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| Authors: | Stevenson Brian von Lackum Kate Wattier Rachel L McAlister Jason D Miller Jennifer C Babb Kelly |
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| Institution: | Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky College of Medicine, MS 415 Chandler Medical Center, Lexington, KY 40536-0298, USA. bstev0@uky.edu |
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| Abstract: | The Lyme disease spirochete, Borrelia burgdorferi, utilizes a LuxS/autoinducer-2-dependent quorum sensing mechanism to control a specific subset of bacterial proteins. It is hypothesized that this system facilitates transmission of B. burgdorferi from feeding ticks into warm-blooded hosts. |
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