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Stereospecific ligands and their complexes. V. Synthesis, characterization and antimicrobial activity of palladium(II) complexes with some alkyl esters of (S,S)-ethylenediamine-N,N′-di-2-propanoic acid |
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| Authors: | Gordana P. Vasi? Ivana D. Radojevi? Ljiljana R. ?omi? Sre?ko R. Trifunovi? |
| Affiliation: | a Department of Chemistry, Faculty of Science, University of Kragujevac, R. Domanovi?a 12, 34000 Kragujevac, Serbia b Department of Biology and Ecology, Faculty of Science, University of Kragujevac, R. Domanovi?a 12, 34000 Kragujevac, Serbia c Faculty of Chemistry, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia |
| Abstract: | Three new ligands and their palladium(II) complexes of general formula [PdCl2(R2-S,S-eddp)] (R = n-propyl, n-butyl and n-pentyl) have been synthesized and characterized by microanalysis, infrared and 1H and 13C NMR spectroscopy. Antimicrobial activity of these ligands and complexes was tested by microdilution method and both minimal inhibitory and microbicidal concentration were determined. These tested complexes demonstrated the significant antifungal activity against pathogenic fungi Aspergillus flavus and Aspergillus fumigatus. On the other hand, these complexes demonstrated moderate antibacterial activity. |
| Keywords: | Palladium(II) complexes (S,S)-ethylenediamine-N,N&prime -di-2-propanoic acid Antimicrobial activity |
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