Widespread N18 in median nerve SEP is preserved in a pontine lesion期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Widespread N18 in median nerve SEP is preserved in a pontine lesion

Institution:	1. FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;2. Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;1. Department of Public Health Research, Kurashiki Clinical Research Institute. Miwa 1-1-1, Kurashiki City, Okayama Prefecture, 710-8602 Japan;2. Systematic Review Workshop Peer Support Group (SRWS-PSG), Japan;3. Department of Otolaryngology-Head and Neck Surgery, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime Prefecture, Japan;1. Institute of Advanced Biomedical Engineering and Science, Tokyo Women''s Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan;2. Department of Cardiology, Tokyo Women''s Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan

Abstract:	Widespread N18 potential to median nerve stimulation was preserved in a patient who had profound unilateral disturbance of deep sensation and a lesion of the pontine medial lemniscus confirmed by MRI. It was concluded from this result that at least a significant part of the N18 potential was generated caudal to the pontine level or at higher levels via extralemniscal pathways. Careful review of studies in man with intraoperative recordings seemed to support that the N18 potential already exists at the medullary level. We suggested that the potential generated at the cuneate nucleus which was described in cats may correspond to part of the N18 potential.

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