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Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
Institution:1. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA;2. Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA;3. Metabolomics Core Facility, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA;4. Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;5. Department of Veterinary Pathobiology, Interdisciplinary Program in Genetics, Texas A&M University, College Station, TX 77843, USA;6. Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA;7. Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA;8. Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA;9. Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA;10. CPRIT Scholar in Cancer Research, Houston, TX, USA
Abstract:
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  • Keywords:mucus-degrading bacteria  allogeneic hematopoietic stem cell transplantation  graft-versus-host disease  broad-spectrum antibiotics  carbapenem  xylose  mucus layer  intestinal microbiome
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