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EMSY inhibits homologous recombination repair and the interferon response,promoting lung cancer immune evasion
Institution:1. Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA;2. Laura and Isaac Perlmutter NYU Cancer Center, New York University Grossman School of Medicine, New York, NY 10016, USA;3. Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA;4. Department of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, NY 10016, USA;5. Howard Hughes Medical Institute, New York University Grossman School of Medicine, New York, NY 10016, USA
Abstract:
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  • Keywords:ubiquitination  immune evasion  EMSY  STING agonsts  BRCAness  PARP inhibitors  KEAP1  lung cancer  NSCLC  interferon
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