Isoniazid therapy of tuberculosis in baboons

A local epizootic of tuberculosis in a laboratory colony of baboons was controlled by 40–80 mg/kg daily dose of Isoniazid. There was definite regression of disease in all animals examined at autopsy, after three weeks and three months of therapy, following their use for unrelated acute experiments. One animal survives in apparent health with a healthy infant that was born after 102 days of therapy.