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The Role of Mitochondria in Stem Cell Biology
Authors:Claudia Nesti  Livia Pasquali  Francesca Vaglini  Gabriele Siciliano  Luigi Murri
Affiliation:(1) CUCCS (Center for the Clinical Use of Stem Cells) and Department of Neurosciences, Section of Neurology , University of Pisa, Via Roma 67, Pisa, 56126, Italy;(2) Department of Neurosciences, Section of Neurology, University of Pisa, Pisa, Italy;(3) Department of Neurosciences, Section of Pharmacology, University of Pisa, Pisa, Italy
Abstract:This mini-review summarizes the current literature on the role of mitochondrial DNA mutations and mitochondrial metabolism in stem cell biology. The possible uses of stem cells as a therapeutic tool in mitochondrial disorders are also reported.
Keywords:Mitochondria  Stem cells  Differentiation  Mitochondrial localization  ROS  MNGIE
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