Regulation of tylosin synthesis in Streptomyces: Effects of glucose analogs and inorganic phosphate |
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Authors: | Norbert Madry Rolf Sprinkmeyer Hermann Pape |
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Institution: | (1) Institut für Mikrobiologie, Universität Münster, D-4400 Münster, Federal Republic of Germany |
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Abstract: | Summary Glucose, 2-deoxy glucose and inorganic phosphate inhibited tylosin production and fatty acid oxidation in Streptomyces T 59–235. Glucose-6-phosphate was accumulated in high-phosphate cultures. The possible function of glucose phosphate as a common mediator of both glucose and phosphate effects is discussed. |
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