Radiation-induced specific locus mutations in human mammary epithelial cells |
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Authors: | M N Gould |
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Abstract: | A specific locus mutagenesis assay using primary cultures of human mammary epithelial cells has been developed. A mutation frequency at the hypoxanthine-guanine phosphoribosyl transferase (HGPRT) locus of approximately 2 X 10(-5) mutations per surviving cell per gray of ionizing radiation was estimated in these cells. |
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