Chromosome localization of two human serine protease genes to region 14q11.2----q12 by in situ hybridization |
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Authors: | C C Lin M Meier O Sorensen R Sasi T Tainaka R C Bleackley |
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Affiliation: | Department of Pathology, University of Alberta, Edmonton, Canada. |
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Abstract: | Two human serine protease genes have been cloned. One corresponds to CTLA1, the human equivalent of the mouse cytotoxic cell protease gene Ctla-1, and the other is novel. Both genes were localized to 14q11.2----q12 by in situ hybridization. This result confirms the assignment of human CTLA1 to 14q11.2----q12 and provides new mapping data for another human serine protease gene located in the same chromosome region. |
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