簇生沿丝伞粗多糖的抗肿瘤活性研究 |
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引用本文: | 丁燕,包海鹰,图力古尔,李玉.簇生沿丝伞粗多糖的抗肿瘤活性研究[J].菌物学报,2006,25(4):611-615. |
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作者姓名: | 丁燕 包海鹰 图力古尔 李玉 |
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作者单位: | 1. 吉林农业大学中药材学院,长春,130118 2. 吉林农业大学菌物研究所,长春,130118 |
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基金项目: | 国家自然科学基金项目(编号30510154)资助 |
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摘 要: | 应用传统多糖提取方法从簇生沿丝伞中获得粗多糖,初步纯化后进行了抗癌活性的体外及体内实验。结果表明,簇生沿丝伞中多糖成分具有很好的抗肿瘤活性,对MCF-7细胞体外细胞增殖抑制率达22.4%,体内抗肝癌抑瘤率达33.79%。
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关 键 词: | 乳腺癌细胞 肝癌 细胞增殖抑制实验 |
文章编号: | 1672-6472(2006)04-0611-0615 |
收稿时间: | 2006-03-07 |
修稿时间: | 2006-06-22 |
Anti-tumor effect of Naematoloma fasciculare polysaccharide |
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Authors: | DING Yan BAO Hai-Ying BAU Tolgor LI Yu |
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Institution: | 1Department of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118; 2Institute of Mycology, Jilin Agricultural University, Changchun 130118 |
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Abstract: | The polysaccharide from fruit bodies of Naematoloma fasciculare was extracted and purified using traditional method. The anti-tumor activity was detected in vitro and in vivo. The inhibition rate of cell growth to MCF-7 cells was 20.4%, and the inhibition rate of tumor growth to hepatic cancer was 33.79% . |
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Keywords: | MCF-7 cell hepatic cancer cell growth inhibition assay |
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