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簇生沿丝伞粗多糖的抗肿瘤活性研究
引用本文:丁燕,包海鹰,图力古尔,李玉.簇生沿丝伞粗多糖的抗肿瘤活性研究[J].菌物学报,2006,25(4):611-615.
作者姓名:丁燕  包海鹰  图力古尔  李玉
作者单位:1. 吉林农业大学中药材学院,长春,130118
2. 吉林农业大学菌物研究所,长春,130118
基金项目:国家自然科学基金项目(编号30510154)资助
摘    要:应用传统多糖提取方法从簇生沿丝伞中获得粗多糖,初步纯化后进行了抗癌活性的体外及体内实验。结果表明,簇生沿丝伞中多糖成分具有很好的抗肿瘤活性,对MCF-7细胞体外细胞增殖抑制率达22.4%,体内抗肝癌抑瘤率达33.79%。

关 键 词:乳腺癌细胞  肝癌  细胞增殖抑制实验
文章编号:1672-6472(2006)04-0611-0615
收稿时间:2006-03-07
修稿时间:2006-06-22

Anti-tumor effect of Naematoloma fasciculare polysaccharide
Authors:DING Yan  BAO Hai-Ying  BAU Tolgor  LI Yu
Institution:1Department of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118; 2Institute of Mycology, Jilin Agricultural University, Changchun 130118
Abstract:The polysaccharide from fruit bodies of Naematoloma fasciculare was extracted and purified using traditional method. The anti-tumor activity was detected in vitro and in vivo. The inhibition rate of cell growth to MCF-7 cells was 20.4%, and the inhibition rate of tumor growth to hepatic cancer was 33.79% .
Keywords:MCF-7 cell  hepatic cancer  cell growth inhibition assay
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