|
|||||
|
|
Pyridone derivatives as potent and selective VLA-4 integrin antagonists |
|
| Authors: | Witherington Jason Bordas Vincent Gaiba Alessandra Green Phil M Naylor Antoinette Parr Nigel Smith David G Takle Andrew K Ward Robert W |
| Affiliation: | Department of Medicinal Chemistry, Neurology & GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Research Limited, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, UK. Jason_Witherington@GSK.com |
| Abstract: | A novel series of pyridone inhibitors has been identified through pharmacophore analysis, as potent antagonists of VLA-4. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |