| 人脑胶质细胞瘤核染色质非组蛋白的聚丙烯酰胺凝胶电泳分析 |
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| 引用本文： | 王瑞珍. 人脑胶质细胞瘤核染色质非组蛋白的聚丙烯酰胺凝胶电泳分析[J]. 中国生物化学与分子生物学报, 1991, 7(1): 79-82 |
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| 作者姓名： | 王瑞珍 |
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| 作者单位： | 江西医学院生化教研室 南昌 |
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| 摘 要： | 用不连续SDS-聚丙烯酰胺凝胶电泳分析了人脑胶质细胞瘤与正常脑细胞核NHCP电泳图谱。从二者的NHCP电泳结果表明,脑胶质细胞瘤增加了一条表观分子量为3万的蛋白区带;表观分子量为1.75万～6.5万的蛋白区带染色明显加深。染色质紫外吸收光谱也有明显差异。总之,脑胶质细胞瘤核NHCP发生质与量的变化。
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| 关 键 词： | 人脑胶质瘤 非组蛋白染色质蛋白质 电泳 聚丙烯酰胺凝胶 |
| 收稿时间： | 1991-02-20 |
Polyacrylamide Slab Gel Electrophoresis of Human Brain Glioma Nonhistone Chromatin Protein (NHCP) |
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| Wang,Rui-zhen. Polyacrylamide Slab Gel Electrophoresis of Human Brain Glioma Nonhistone Chromatin Protein (NHCP)[J]. Chinese Journal of Biochemistry and Molecular Biology, 1991, 7(1): 79-82 |
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| Authors: | Wang Rui-zhen |
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| Affiliation: | (Department of Biochemistry. Jiangxi Medical college,Nanchang 330006 |
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| Abstract: | The electrophoretogram of brain nonhistone chromatin protein (NHCP)from human brain glioma and normal human brain were analyzed by SDS polyacrylamide slab gel electrophoreses. Analytical results showed that a new NHCP band (apprpx. 30000mol. wt. ) was found in human brain glioma, other regions (approx, 17500-65000mol. wt. ) were deeply stained indication marked increase in human brain glioma. In general,NHCP of brain nucleus of human glioma was changed both in quantity and in quality. |
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| Keywords: | Human Glioma Nonhistone Chromatin Protein Electrophoresis Polyacrylamide Gel |
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