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Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment
Authors:Wiley Jesse C  Hudson Mark  Kanning Kevin C  Schecterson Leslyanne C  Bothwell Mark
Institution:Department of Physiology and Biophysics, University of Washginton, Seattle, Washington 98195, USA.
Abstract:
Keywords:Alzheimer's disease  β-amyloid precursor protein  cleavage  familial Alzheimer's disease  γ-secretase  presenilin
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