Lead and Arsenic Levels in Women with Different Body Mass Composition |
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Authors: | Ana Maria Ronco Yareni Gutierrez Nuri Gras Luis Muñoz Gabriela Salazar Miguel N Llanos |
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Institution: | (1) Laboratory of Nutrition and Metabolic Regulation, Institute of Nutrition and Food Technology, INTA, University of Chile, Macul, 5540 Santiago, Chile;(2) Department of Metrology, Chilean Commission of Nuclear Energy, CCHEN, La Reina, Santiago, Chile;(3) Institute of Nutrition and Food Technology, INTA, University of Chile, Macul, 5540 Santiago, Chile |
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Abstract: | The objective of this study was to evaluate whether lead (Pb) and arsenic (As) levels in biological fluids were associated
to the body composition in a group of reproductive-age women. Voluntary childbearing-age women (n = 107) were divided into three groups according to their body mass index (BMI: weight/height2 (kg/m2): low weight (BMI<18.5 kg/m2), normal $ \left( {{\text{BMI}} > 19\kern1.5pt<\kern1.5pt24.9\,{{\text{kg}} \mathord{\left/{\vphantom {{\text{kg}} {{{\text{m}}^{\text{2}}}}}} \right.} {{{\text{m}}^{\text{2}}}}}} \right) $ \left( {{\text{BMI}} > 19\kern1.5pt<\kern1.5pt24.9\,{{\text{kg}} \mathord{\left/{\vphantom {{\text{kg}} {{{\text{m}}^{\text{2}}}}}} \right.} {{{\text{m}}^{\text{2}}}}}} \right) , and overweight (BMI>25 kg/m2). Body composition and fat mass percentage were determined by the isotopic dilution method utilizing deuterated water. Blood
lead concentrations were determined by graphite furnace atomic absorption spectrometry and urinary arsenic (AsU) concentrations
by inductively coupled plasma mass spectrometry. The type and frequency of food consumption and lifestyle-related factors
were also registered. Most women had $ {\text{PbB}}\,{\text{levels}} > 2\kern1.5pt<\kern1.5pt10\,{\mu{{\text{ g}}} \mathord{\left/{\vphantom {\mu{{\text{ g}}} {\text{dL}}}} \right.} {\text{dL}}} $ {\text{PbB}}\,{\text{levels}} > 2\kern1.5pt<\kern1.5pt10\,{\mu{{\text{ g}}} \mathord{\left/{\vphantom {\mu{{\text{ g}}} {\text{dL}}}} \right.} {\text{dL}}} , and only 2.6% had AsU concentrations above 50 μg/L. The levels of these toxic elements were not found to be associated with
the fat mass percentage. |
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