Virulence factors of schistosomes |
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| Authors: | R. Alan Wilson |
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| Affiliation: | 1. Department of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, St Mary''s Campus, London, UK;4. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK;5. Department of Pathology and Pathogen Biology, Centre for Emerging, Endemic and Exotic Diseases (CEEED), Royal Veterinary College, University of London, London, UK |
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| Abstract: | This review considers whether the products of schistosomes in the mammalian host can be considered as virulence factors. These include: the cercarial secretions used in infection, those of the migrating schistosomulum, surface-exposed proteins of adult worms in the portal system and their gut vomitus in the context of immune evasion, secretions of the egg facilitating its escape from gut tissues and micro-exon gene products. |
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