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Differential expression of bcl-2 and bcl-x during chicken spermatogenesis
Authors:X. Vilagrasa  C. Mezquita  J. Mezquita
Abstract:We report the isolation and characterization of a chicken testis bcl-xL cDNA coding for a long bcl-x protein with a hydrophobic tail, and the expression of bcl-2 and bcl-x during chicken spermatogenesis. Bcl-2 is highly expressed in embryonic and immature testes enriched in spermatogonia and barely detectable in mature testes, where most of the cells are meiotic and postmeiotic. Bcl-x is expressed in both mature and immature testes, but in a lesser amount in mature testes. Differential expression of bcl-2 and bcl-x during spermatogenesis is consistent with the reported different susceptibility to apoptosis of spermatogonia, and meiotic and postmeiotic cells. Mol. Reprod. Dev. 47:26–29, 1997. © 1997 Wiley-Liss, Inc.
Keywords:gene expression  testis  apoptosis  spermatogonia  meiotic and postmeiotic cells  anchored bcl-x protein
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