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Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability
Authors:Zixing Fu  Fang Liu  Chunyue Liu  Beifang Jin  Yueqing Jiang  Mingliang Tang  Xin Qi  Xing Guo
Affiliation:1. Department of Neurobiology, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, Jiangsu, China;2. Department of Anatomy, College of Basic Medicine, Guilin Medical University, Guilin 541004, China;3. Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing 210096, China;4. Department of Physiology & Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA;5. Center for Mitochondrial Disease, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
Abstract:
Keywords:Correspondence to: X. Qi, Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, 10900 Euclid Ave, E516, Cleveland, OH 44106–4970, USA.  Huntington's disease  ABCB10  Mitochondrial unfolded protein response  Mitochondrial dysfunction
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