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Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition |
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| Authors: | Bartlomiej J. Blus Hideharu Hashimoto Hyuk-Soo Seo Aleksandra Krolak Erik W. Debler |
| Affiliation: | 1. Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA;2. Department of Biochemistry & Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA;3. Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA |
| Abstract: |  |
| Keywords: | Corresponding author chromatin epigenetics bromodomain histone tails lysine acetylation chromatin remodeling substrate specificity binding promiscuity X-ray crystallography isothermal titration calorimetry |
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