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Expert research on sera yielding false-positive results for HIV antibodies during screening]
Authors:F S Noskov  T T Smol'skaia  R E Konikova  V V Borisova  N P Leshchinskaia  O V Noskova  A L Lobanova  S S Marennikova  G R Matsevich  E M Shelukhina
Abstract:The significance of different serological methods and assay systems for the verification of false positive cases of HIV infection has been analyzed on the basis of materials obtained in arbitration studies. As demonstrated by this analysis, the use of such highly specific and sensitive systems as Huma-Lab, Enzygnost, Serodia and Erythrorecombinant has made it possible to obtain a reliable result as early as at the first stage of expert diagnosis in the enzyme immunoassay and the agglutination test. The methods of radioimmunoprecipitation and indirect immunofluorescence have permitted a more precise differentiation of doubtful results than that achieved by immune blotting.
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