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Phomoxins B and C: polyketides from an endophytic fungus of the genus Eupenicillium |
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| Authors: | Davis Rohan A Andjic Vesna Kotiw Michael Shivas Roger G |
| Affiliation: | Chemical Biology Program, Eskitis Institute, Griffith University, Brisbane, Qld 4111, Australia. r.davis@griffith.edu.au |
| Abstract: | Chemical investigations of the culture broth from an endophytic fungus Eupenicillium sp. have afforded two natural products phomoxins B (1) and C (2) as well as the previously reported fungal metabolite eupenoxide (3). Compounds 1 and 2 both contain a cyclic carbonate moiety that is rare among natural products. This paper reports the full spectroscopic characterisation of phomoxins B (1) and C (2) by NMR, UV, IR and MS data. All compounds were inactive against a panel of nosocomial microbes. |
| Keywords: | Endophytic fungus Eupenicillium sp. Glochidion ferdinandi Natural products Polyketides Phomoxin B Phomoxin C Eupenoxide Cyclic carbonate |
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