Determinants of Fatigue after First-Ever Ischemic Stroke during Acute Phase |
| |
Authors: | Shan-Shan Wang Jia-Ji Wang Pei-Xi Wang Ruoling Chen |
| |
Affiliation: | 1. Institute of Public Health, School of Nursing, Henan University, Kaifeng, China.; 2. Department of Preventive Medicine, School of Public Health, Guangzhou Medical University, Guangzhou, China.; 3. Department of Primary Care and Public Health Sciences, King’s College London, London, United Kingdom.; 4. Centre for Health and Social Care Improvement (CHSCI), University of Wolverhampton, Wolverhampton, United Kingdom.; University of Glasgow, United Kingdom, |
| |
Abstract: | Background and PurposeFatigue after stroke is common and has a negative impact on rehabilitation and survival. However, its pathogenesis and contributing factors remain unclear. The purpose of this study was to identify factors influencing the occurrence of fatigue after first-ever ischemic stroke in acute phase.MethodsWe examined 265 consecutive patients with first-ever ischemic stroke during acute phase (within 2 weeks) in two tertiary stroke care hospitals in Henan, China. We documented patients’ demographic and clinical characteristics through face-to-face interviews using structured questionnaires and reviews of medical records. Post-stroke fatigue was defined as a score of ≥4 using the Fatigue Severity Scale. Multivariate logistic regression was used to examine post-stroke fatigue in relation to socio-demographic, lifestyle, clinical characteristics and family function.ResultsAbout 40% first-ever ischemic stroke patients experienced post-stroke fatigue in acute phase. Post-stroke fatigue was associated with lack of exercise before stroke (adjusted odds ratio 4.01, 95% CI 1.95–8.24), family dysfunction (2.63, 1.20–5.80), depression (2.39, 1.02–5.58), the presence of pre-stroke fatigue (4.89, 2.13–11.21), use of sedative medications (4.14, 1.58–10.88), coronary heart disease (3.38, 1.46–7.79) and more severe Modified Rankin Scale (2.55, 1.65–3.95).ConclusionsThe causes of post-stroke fatigue are multifaceted. More physical exercise, improving family function, reducing depression and appropriate use of sedative medications may be helpful in preventing post-stroke fatigue. |
| |
Keywords: | |
|
|