Influence of the menopause and aging on spinal density in French women |
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| Institution: | 1. GIGA In Silico Medicine, University of Liege, Liege, Belgium;2. Departamento de Engenharia Mecatrônica e de Sistemas Mecânicos, University of São Paulo, São Paulo, Brazil;3. Departamento de Engenharia Mecânica, University of São Paulo, São Paulo, Brazil;4. Mechanical Engineering, Centre of Bio-Engineering, University of Canterbury, Christchurch, New Zealand |
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| Abstract: | Dual photon absorptiometry (DPA) was used to measure the bone mineral density (BMD) of the lumbar spine in 510 normal women from the south of France. Long-term precision was 2.2%. BMD was stable in young adults and again in women over 70 years of age. Perimenopausal women at an average age of 51 years already evidenced a slight bone diminution (5%) compared to young adults and women within 2 years of the menopause already had a 10% diminution. The average rate of apparent bone loss in this cross-sectional study was 1% per year from age 45 to 65 years, but about 75% of this decrease occurred in the first decade after the menopause. Spinal BMD in our normal French population appears to be 5–10% lower than US values. |
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