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Vertebral morphometry in diagnosis of spinal fractures
Institution:1. Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy;2. Department of Medicine, Endocrinology, Metabolism and Geriatrics, Azienda USL of Modena, Modena, Italy;3. HIV Metabolic Clinic, Infectious and Tropical Disease Unit, Department of Medical and Surgical Sciences for Adults and Children, University of Modena and Reggio Emilia, Modena, Italy;1. Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, IL, USA;2. Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois School of Medicine, Springfield, IL, USA;1. School of Medicine, Baylor College of Medicine, Houston, Texas, USA;3. Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA;2. Department of Bioengineering, UT Arlington, Arlington, Texas, USA;4. Department of Surgery, American University of Beirut, Riad El-Solh, Beirut, Lebanon;1. Resident, Discipline of Orthodontics, Department of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand;2. PhD candidate, Department of Computer Science, University of Otago, Dunedin, New Zealand;3. Formerly, professor, Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand;4. Professor and chair, Discipline of Orthodontics, Department of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin, New Zealand;1. Clinique Victor-Hugo, 5, rue du Dôme, 75116 Paris, France;2. Department of Orthopaedic Surgery, hôpital Ambroise-Paré, hôpitaux universitaires Paris-Ile-de-France-Ouest, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France
Abstract:Vertebral morphometry was performed on lateral thoracic and lumbar radiographs of 153 women with a preliminary diagnosis of spinal osteoporosis. Measurements included anterior and posterior vertebral height, width, area, wedge angle, percent reduction of anterior to posterior height (PRH) and percent difference in anterior height between adjoining vertebrae (PDAH). A vertebral fracture was identified if any of the measurements which control for interindividual variation in vertebral size (wedge angle, PRH, PDAH) were below the normal range.Among individuals with mild osteoporosis (0–2 fractures) PDAH identified 86% of the fractures and 95% of the individuals with fractures. Other measurements identified less than 71% of the fractures and less than 80% of the individuals with fractures. Although the results reflect a relative rather than a true sensilivity it appears that PDAH is the better diagnostic measurement for fractures in the earlier stages of spinal osteoporosis.
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