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Computational and transcriptional evidence for microRNAs in the honey bee genome
Authors:Daniel B Weaver  Juan M Anzola  Jay D Evans  Jeffrey G Reid  Justin T Reese  Kevin L Childs  Evgeny M Zdobnov  Manoj P Samanta  Jonathan Miller  Christine G Elsik
Affiliation:(1) Bee Power, LP, Lynn Grove Road, 16481 CR 319 Navasota, TX 77868, USA;(2) Department of Animal Science, College Station, Texas A&M University, Texas, 77843, USA;(3) Bee Research Laboratory, BARC-E, USDA-ARS, Beltsville, MD, USA;(4) WM Keck Center for Interdisciplinary BioScience Training, Houston, TX 77005, USA;(5) European Molecular Biology Laboratory, Meyerhofstr, Heidelberg, Germany;(6) Systemix Institute, Los Altos, CA 94024, USA;(7) Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA;(8) The Institute for Genome Research, Rockville, MD 20850, USA;(9) Department of Genetic Medicine and Development, University of Geneva Medical School (CMU), rue Michel-Servet 1, 1211 Geneva 4, Switzerland
Abstract:

Background  

Non-coding microRNAs (miRNAs) are key regulators of gene expression in eukaryotes. Insect miRNAs help regulate the levels of proteins involved with development, metabolism, and other life history traits. The recently sequenced honey bee genome provides an opportunity to detect novel miRNAs in both this species and others, and to begin to infer the roles of miRNAs in honey bee development.
Keywords:
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