| 丹参水溶性成分的地域分布特点分析 |
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| 引用本文： | 杨新杰,万德光,刘敏,林贵兵,王金燕,严铸云.丹参水溶性成分的地域分布特点分析[J].天然产物研究与开发,2011,23(4):684-688. |
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| 作者姓名： | 杨新杰 万德光 刘敏 林贵兵 王金燕 严铸云 |
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| 作者单位： | 成都中医药大学药学院中药材标准化教育部重点实验室,成都,610075 |
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| 基金项目： | 国家十一五科技支撑计划项目 |
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| 摘 要： | 分析全国不同产地丹参中水溶性成分的含量变化情况及其地域分布特点。采用HPLC法测定不同产地丹参水溶性成分的含量,运用SAS统计软件分析丹参水溶性成分相关性及其地域分布特点。回归分析表明,丹参素与丹酚酸A含量呈负相关,原儿茶醛与迷迭香酸含量呈负相关,咖啡酸与丹参素含量呈负相关,丹酚酸B与丹酚酸A、丹参素含量呈正相关。聚类分析表明,三个野生药材与山东和河南大部分产地、四川中江栽培药材水溶性成分较高聚为一类。建议丹参药材中丹参素≥0.14%,原儿茶醛≥0.01%,咖啡酸≥0.01%,迷迭香酸≥0.17%,丹酚酸B≥3.0%,丹酚酸A≥0.01%。丹参的水溶性成分呈现地域性差异,传统道地产区的含量较高。
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| 关 键 词： | 丹参 丹参素 原儿茶醛 咖啡酸 迷迭香酸 丹酚酸B 丹酚酸A HPLC |
Analysis on Geographical Distribution of Hydrophilic Components in Radix Salviae Miltiorrhizae |
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| YANG Xin-jie,WAN De-guang,LIU Min,LINGui-bing,WANG Jin-yan,YAN Zhu-yun.Analysis on Geographical Distribution of Hydrophilic Components in Radix Salviae Miltiorrhizae[J].Natural Product Research and Development,2011,23(4):684-688. |
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| Authors: | YANG Xin-jie WAN De-guang LIU Min LINGui-bing WANG Jin-yan YAN Zhu-yun |
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| Institution: | YANG Xin-jie,WAN De-guang,LIU Min,LIN Gui-bing,WANG Jin-yan,YAN Zhu-yun College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Key Laboratory of Standardization of Chinese Herbal Medicines of Ministry of Education,Chengdu 610075,China |
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| Abstract: | Analyzing the content change of hydrophilic constituents and it's geographical distribution in Salvia miltiorrhira from different producing area around china.Determining content of hydrophilic constituents in S.miltiorrhira from different producing area by HPLC and using SAS to analyze correlation about hydrophilic constituents in S.miltiorrhira and it's geogrofic distribution.Regression analysis shows that content of Danshensu and salvianolic acid A present negative correlation,protocatechuic aldehyde and ... |
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| Keywords: | Radix Salviae Miltiorrhizae danshensu protocatechuic aldehyde caffeic acid rosemarinic acid salvianolic acid B salvianolic acid A HPLC |
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