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| 江西青霉的次生代谢产物研究 | |
| 引用本文： | 陈超,潘卫东,肖建辉,梁光义.江西青霉的次生代谢产物研究[J].天然产物研究与开发,2011,23(4):664-666. |
| 作者姓名： | 陈超 潘卫东 肖建辉 梁光义 |
| 作者单位： | 1. 贵州大学,贵阳550025;贵州省中国科学院天然产物化学重点实验室,贵阳550002 2. 贵州省中国科学院天然产物化学重点实验室,贵阳,550002 3. 遵义医学院贵州省细胞工程重点实验室,遵义,563003 4. 贵州省中国科学院天然产物化学重点实验室,贵阳550002;贵阳中医学院,贵阳550002 |
| 基金项目： | 国家自然科学基金，贵州省优秀青年科技人才培养支持计划，贵州省科学技术基金 |
| 摘 要： | 江西青霉是药用江西虫草的无性型,本文对江西青霉发酵菌丝体甲醇提取物的正丁醇萃取部位运用反复色谱层析进行了系统的分离纯化,得到了6个化合物。经波谱解析,并结合理化鉴定,确定这6个化合物结构为尿嘧啶(1)2、’-脱氧尿嘧啶核苷(2)、腺嘌呤(3)、腺苷(4)、L-焦谷氨酸甲酯(5)和2’-甲氧基腺苷(6)。其中化合物2、5和6为首次从虫草属中分离获得的化合物。 |
| 关 键 词： | 江西青霉 次生代谢产物 分离纯化 结构鉴定 |
Secondary Metabolites of Penicillium jiangxiense |
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| CHEN Chao,PAN Wei-dong,XIAO Jian-hui,LIANG Guang-yi.Secondary Metabolites of Penicillium jiangxiense[J].Natural Product Research and Development,2011,23(4):664-666. | |
| Authors: | CHEN Chao PAN Wei-dong XIAO Jian-hui LIANG Guang-yi |
| Institution: | CHEN Chao1,2,PAN Wei-dong2,XIAO Jian-hui3,LIANG Guang-yi2,4 1Guizhou University,Guiyang 550025,China,2The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences,Guiyang 550002,3Key Laboratory of Cell Engineering of Guizhou Province,Zunyi Medicinal College,Zunyi 563003,4Guiyang College of Traditional Chinese Medicine |
| Abstract: | The chemical constituents of the n-butanol extractive of the mycelium of Penicillium jiangxiense,the anamorph of medicinal Cordyceps jiangxiensis,were separated and purified by various chromatographic techniques.Six compounds were obtained and their structures were elucidated on the basis of spectral analysis as uracil(1),2′-deoxyuridine(2),adenine(3),adenosine(4),methyl L-pyroglutamate(5),2′-O-methyladenosine(6),of which compounds 2,5 and 6 were isolated from Cordyceps species for the first time. |
| Keywords: | Penicillium jiangxiense secondary metabolites purification Structural identification |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |