Correlation of the fibrinogen level with blood pressure and plasma renin activity in rats with early Goldblatt hypertension |
| |
| Authors: | S Sonkodi I Sohár E Stumpf |
| |
| Affiliation: | First Department of Medicine, University Medical School, Szeged, Hungary. |
| |
| Abstract: | Goldblatt hypertension was induced in rats by constricting the renal artery on one side. In one group of animals the contralateral kidney remained untouched (two-kidney hypertension), while in the other it was removed (one-kidney hypertension). In the two-kidney hypertension group, renin activity was higher than in the control animals, the fibrinogen was normal both in arterial and venous blood while in one-kidney hypertension the PRA was normal, but the fibrinogen was increased. A close significant correlation could be demonstrated between blood pressure and fibrinogen. |
| |
| Keywords: | |
|
|
