Elevated levels of prostaglandin e2 and thromboxane B2 in depression |
| |
| Affiliation: | 1. The pharmaceutical school of Youjiang medical university for nationalities, Baise 533000, China;2. The key laboratory of Guangxi colleges and universities in Youjiang river drainage area for studying traditional Chinese medicinal herbs (folk medicine), Baise 533000, China;3. The affiliated hospital of Youjiang medical university for nationalities, Baise 533000, China |
| |
| Abstract: | Plasma prostaglandin E2 (PGE2) and thromboxane B2 (TXB2) levels were measured in 30 depressed outpatients. Plasma PGE2 was increased in all but one of these patients (p<0.001) and all had increased levels of TXB2 (p<0.001). Since monamine oxidase inhibitors inhibit brain prostaglandin synthesis, and tricyclic antidepressants may antagonize prostaglandin actions, these observations suggest new approaches to depression research. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
