Perylene attached to DNA through stiff or flexible linker: duplex stability and FRET |
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Authors: | Skorobogatyj Mikhail V Pchelintseva Anna A Ustinov Alexei V Korshun Vladimir A Malakhov Andrei D |
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Institution: | Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. |
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Abstract: | Two fluorescent nucleosides, 5-(perylen-3-ylethynyl)-2'-deoxyuridine and 5-(perylen-3-yl)methoxypropyn-1-yl]-2'-deoxyuridine, were incorporated into synthetic oligodeoxyribonucleotides and spectral properties of the conjugates and their duplexes were studied. |
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