Red cell glucose-6-phosphate dehydrogenase deficiency and haemoglobin variants among ten endogamous groups of Maharashtra and West Bengal |
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Authors: | S L Kate B N Mukherjee K C Malhotra M A Phadke G S Mutalik G S Sainani |
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Institution: | (1) Genetic Division, Department of Medicine and Biochemistry, B. J. Medical College, Poona, India;(2) Indian Statistical Institute, 203 B. T. Road, Calcutta, India |
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Abstract: | Summary Over 900 individuals from ten endogamous groups in the Indian states of Maharashtra and West Bengal were studied for G-6-PD deficiency and haemoglobin variants. The incidence of G-6-PD varied from nil to 17.3%, while that of Hb-S varied from nil to 22.3%. In general, the tribal populations of Maharashtra are characterized by the presence of a high incidence of both Hb-S and G-6-PD deficiency. The caste Hindus showed an absence of Hb-S and rather low G-6-PD deficiency. Immigrant Parsis possessed the highest incidence of G-6-PD deficiency (17.3%). |
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