A metabolite fingerprinting for the characterization of commercial botanical dietary supplements |
| |
Authors: | Luisa Mattoli Francesca Cangi Caterina Ghiara Michela Burico Anna Maidecchi Erika Bianchi Eugenio Ragazzi Lisa Bellotto Roberta Seraglia Pietro Traldi |
| |
Institution: | (1) Research Area, Aboca S.p.A. Societ? Agricola, Loc. Aboca, Sansepolcro, AR, Italy;(2) Department of Pharmacology and Anesthesiology, University of Padova, Largo Meneghetti 2, Padova, Italy;(3) CNR-ISTM, Corso Stati Uniti 4, Padova, Italy |
| |
Abstract: | Phytopharmaceuticals, phytomedicines and botanical dietary supplements are products of wide interest considering the increase
of their use. The development of fast and effective analytical methods able to give a fingerprinting of the product, on the
basis of the plant extracts declared to be contained in it, is surely of high interest. In a previous investigation electrospray
mass spectrometry was proved to be effective for the characterization of plant extracts. The direct infusion of the samples
and the analyses in both positive and negative ion mode lead to a clear differentiation of the different samples. To verify
if the same approach can be effective also for mixtures of plant extracts, five different commercial dietary supplements Sedivitax gocce (1), Finocarbo Plus opercoli (2), Sollievo Bio tavolette (3), MiniMas opercoli (4) and Ruscoven gocce (5), all products from Aboca S.p.A., Sansepolcro, Italy] were analyzed by ESI. In order to evaluate possible changes in the
metabolic profile with respect to different years of production, ten different batches of the commercial dietary supplements
were considered. The mass spectral data were evaluated by multivariate analysis and the obtained results suggest that the
method allows a satisfactory and rapid characterization of complex mixtures of commercial dietary supplements. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|