Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates |
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| Authors: | Centurion-Lara A Sun E S Barrett L K Castro C Lukehart S A Van Voorhis W C |
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| Affiliation: | Departments of Medicine and Pathobiology, University of Washington, Seattle, Washington 98195-7185, USA. |
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| Abstract: | Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7 of 8 non-pallidum isolates, and tprD3 is found in one T. pallidum subsp. pertenue isolate. Antibodies against TprD2 are found in persons with syphilis, demonstrating that tprD2 is expressed during infection. |
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