酪酸梭菌活菌散在迟发型母乳性黄疸中的应用

目的探讨酪酸梭菌活菌散促进迟发型母乳性黄疸消退的疗效。方法将87例迟发型母乳性黄疽患儿随机分为对照组和观察组，对照组43例和观察组44例，对照组采用常规治疗，观察组在常规治疗的基础上加服酿酸梭菌活菌散,500mg/次，3次/d，两组均不停止母乳喂养。观察两组患儿日均胆红素水平的变化及黄疽消退时间。结果观察组日均胆红素下降程度显著大于对照组（P〈0. 01）,观察组黄疸消退时间明显短于对照组（P〈0. 01），差异有统计学意义。结论在常规治疗的基础上加用酪酸梭菌活菌散治疗迟发型母乳性黄疸，不仅可加速胆红素降低水平，缩短黄疽持续时间，而且能显著缓解茵扼黄颗粒引起的腹泻，是一种简单、安全、有效的治疗措施,并减少停喂母乳对乳母及乳儿的不利影响,值得临床推广应用。

Clostridium butyricum powder in treatment of Late-onset Breast MiIk Jaundice

Objective To investigate the effect of Clostridium butyricum powder to promote Lateonset Breast Milk Jaundice （LB-MJ） regression. Methods 87 cases children of Lateonset Breast Milk Jaundice were randomly divided into control group （ n = 43 ） andobservation group （ n =44） . All children received conventional treatment and didn＇t stop breast feeding during treatment. In the observation group, Clostridium butyricum powder was administered in doses of 500 mg three times a day. Results Compared to the controlgroup, the daily average value of declining of bilirubin in observation group was significantly higher （P 〈0. 01 ）,and the days of persistent jaundice was significantly shorter （P 〈0. 01 ） . Conclusion Clostridium butyricum powder combined with conventional treatment intreatment of LBMJ,not only can accelerate bilirubin reduced level and shorten the duration of jaundice, but also can significantly relievediarrhea caused by Yinzhihuang granules.