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In Vitro Effect of Tetanus Toxin on GAB A Release from Rat Hippocampal Slices

Authors:	G L Collingridge P A Thompson† J Davies J Mellanby†

Institution:	School of Pharmacy, University of London, London, United Kingdom;Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom

Abstract:	Abstract Ca²⁺-dependent K⁺-stimulated γ-aminobutyric acid release from rat hippocampal slices was reduced about 30% by pre-incubation of the slices with 10⁴ mouse LD₅₀/ml tetanus toxin for 3 h at 37°C.

Keywords:	Tetanus toxin γ-Aminobutyric acid