Computational models of heart pumping efficiencies based on contraction waves in spiral elastic bands |
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Authors: | Anna Grosberg Morteza Gharib |
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Affiliation: | a Option in Bioengineering, California Institute of Technology (Caltech), Pasadena, CA, USA b Graduate Aeronautical Laboratories, California Institute of Technology (Caltech), Pasadena, USA |
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Abstract: | We present a framework for modeling biological pumping organs based on coupled spiral elastic band geometries and active wave-propagating excitation mechanisms. Two pumping mechanisms are considered in detail by way of example: one of a simple tube, which represents a embryonic fish heart and another more complicated structure with the potential to model the adult human heart. Through finite element modeling different elastic contractions are induced in the band. For each version the pumping efficiency is measured and the dynamics are evaluated. We show that by combining helical shapes of muscle bands with a contraction wave it is possible not only to achieve efficient pumping, but also to create desired dynamics of the structure. As a result we match the function of the model pumps and their dynamics to physiological observations. |
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Keywords: | Cardiac modeling Left ventricular twist Myocardium macro-structure Finite element simulations |
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