Chlamydia trachomatis: identification of susceptibility markers for ocular and sexually transmitted infection by immunogenetics |
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| Authors: | Servaas A. Morré ,Ouafae Karimi,& Sander Ouburg |
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| Affiliation: | Laboratory of Immunogenetics, Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands;and;Department of Medical Microbiology, Maastricht University Medical Center, Maastricht, The Netherlands |
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| Abstract: | The aim of this review is to present a concise overview of all data available on the immunogenetics of Chlamydia trachomatis infections, both sexually transmitted urogenital and ocular infections. Currently, candidate gene approaches are used to identify genes related to the susceptibility to and severity of C. trachomatis infections. The main focus in the review will be on data obtained by the study of human cohorts. |
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| Keywords: | Chlamydia trachomatis infections immunogenetics single-nucleotide polymorphisms pathogen recognition receptors Toll-like receptors cytokines |
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