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Genome Structure and Evolution of Naegleria and its Relatives
Authors:C GRAHAM CLARK
Institution:Laboratory of Molecular Parasitology. The Rockefeller University, 1230 York Avenue, New York, New York 10021
Abstract:In the 4 yr since the molecular biology of DNA in Naegleria was last reviewed several major advances have been made, and these are reviewed here: isolation and characterization of mitochondrial and ribosomal DNAs; enumeration of chromosomal DNAs by pulsed field gel electrophoresis; sequence analysis of differentially expressed genes; phylogenetic placement of the genus Naegleria among the eukarayotes and Naegleria species within the genus.
Keywords:Chromosome  mitochondrial DNA  plasmid  pulsed-field gel electrophoresis  ribosomal DNA
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