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Ganoderic acid produced from submerged culture of |
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| Authors: | Hai-long?Yang author-information" > author-information__contact u-icon-before" > mailto:yanghl@yahoo.com" title=" yanghl@yahoo.com" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
| Affiliation: | (1) School of Life & Environmental Science, Wenzhou University, Middle Xueyuan Road, 325000 Wenzhou, People’s Republic of China |
| Abstract: | Ganoderic acid (GA), produced by submerged culture of Ganoderma lucidum, at 500 μg/ml, caused nearly a 70% inhibition of the growth of human hepatoma cell line BEL7402 but not of a normal human liver cell line L02. Flow cytometry analyses showed that GA blocked the BEL7402 cell cycle at the transition from G1 to S phase. |
| Keywords: | cell cycle cytotoxicity Ganoderma lucidum hepatoma submerged culture |
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