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Roles of the Pribnow box in positive regulation of the ompC and ompF genes in Escherichia coli.
Authors:Y Ozawa   T Mizuno     S Mizushima
Abstract:The roles of the first base of the Pribnow box in positive regulation of the ompC and ompF genes were studied. G- and A-to-T substitutions of the first base of the ompC and ompF Pribnow boxes, respectively, resulted in a high-level functioning of the promoters in the ompR background. The level was further enhanced significantly in the ompR+ background. The effects of other substitutions were also studied. Based on these observations, the roles of the Pribnow box in the positive regulation are discussed.
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